Environmental temperature and choline requirement in rats. I: Choline deficiency in rats at various temperatures
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Renal Lesions in Choline Deficiency in Rats
DURING the course of experiments with rats fed on a vitamin A deficient diet deaths occurred from a haemorrhagic degeneration of the kidneys. lThe changes foun(] in the kidneys resembled those described in choline deficiency by Griffith and Wade (1939). In their experiments the hwmorrhagic renal lesion was always accompanied by marked fatty degeneration of the liver, xvhile in our experiments t...
متن کاملThe Choline Content of Rats on Various Choline-free Diets*
Choline synthesis in the rat is intimated by the fact that methionine can replace choline in preventing fatty livers (l), and by the observation that labeled methyl groups can be transferred from methionine to choline (2). However, the development of fatty livers (3) and of hemorrhagic kidneys (4) and the restricted growth (5, 6) in rats on low choline diets all suggest that preformed choline m...
متن کاملPrenatal choline deficiency increases choline transporter expression in the septum and hippocampus during postnatal development and in adulthood in rats.
Supplementation of maternal diet with the essential nutrient, choline, during the second half of pregnancy in rats causes long-lasting improvements in spatial memory in the offspring and protects them from the memory decline characteristic of old age. In contrast, prenatal choline deficiency is associated with poor performance in certain cognitive tasks. The mechanism by which choline influence...
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Dolly, J. O., Dillon, A., Duffy, M. J. & Fottrell, P. F. (1971) Clin. Chim. Actu 31, 55-62 Donlon, J. & Fottrell, P. F. (1971) Clin. Chim. Acta 33, 345-350 Donlon, J. & Fottrell, P. F. (1972) Cornp. Biochem. Physiol. B 41, 181-193 Fogel, M. R. & Adibi, S. A. (1974) J. Lab. Clin. Med. 84, 327-333 OCuinn, G. & Fottrell, P. F. (1975) Biochem. Soc. Trans. 3, 1219-1221 OCuinn, G., Piggott, C. 0. & F...
متن کاملLipoproteins in choline deficiency.
Choline deficiency leads to lipomatous infiltration of the coronary arteries and to aortic sclerosis of the Moenckeberg type in young rats. In this form of experimental cardiovascular disease the total serum cholesterol and the triglyceride-bearing lipoproteins are decreased. The beta-lipoprotein classes are essentially within normal limits. The significance of these findings in particular and ...
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ژورنال
عنوان ژورنال: Journal of Lipid Research
سال: 1966
ISSN: 0022-2275
DOI: 10.1016/s0022-2275(20)39579-1